Genesis is the most popular WordPress framework on the market.
Not only do they offer a comprehensive offering of WordPress themes for your business, their framework empowers you to build sites more efficiently. There is one caveat, however. You still need to be a developer to create custom layouts for your content. Sure, you can dig through their vast and well documented support pages, but sometimes you need a solution that will do it for you.
You can do this with the Genesis add-on for Conductor.